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Another option, yet still not investigated is the ability of esophageal luminal content (e.g., intraesophageal menthol) to affect the contraction amplitude due to the proximity of afferent (e.g., TRPM8) receptors to the esophageal luminal surface

[19] [20] In fact, menthol tobacco marketing is specifically targeted to African Americans

People are increasingly opting to use cheaper hand-rolled tobacco over more expensive manufactured cigarettes, proving that consistency in the taxation and regulation across all cigarette types is key

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This observation seems to imply that the mice inhaled a greater total amount of CS when menthol vapor was added to the smoke